Cargando…

Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies

Many efforts targeting amyloid‐β (Aβ) plaques for the treatment of Alzheimer's Disease thus far have resulted in failures during clinical trials. Regional and temporal heterogeneity of efficacy and dependence on plaque maturity may have contributed to these disappointing outcomes. In this study...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirschenbaum, Daniel, Dadgar‐Kiani, Ehsan, Catto, Francesca, Voigt, Fabian F, Trevisan, Chiara, Bichsel, Oliver, Shirani, Hamid, Nilsson, K Peter R, Frontzek, Karl J, Paganetti, Paolo, Helmchen, Fritjof, Lee, Jin Hyung, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832821/
https://www.ncbi.nlm.nih.gov/pubmed/36382364
http://dx.doi.org/10.15252/emmm.202216789