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Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies
Many efforts targeting amyloid‐β (Aβ) plaques for the treatment of Alzheimer's Disease thus far have resulted in failures during clinical trials. Regional and temporal heterogeneity of efficacy and dependence on plaque maturity may have contributed to these disappointing outcomes. In this study...
Autores principales: | Kirschenbaum, Daniel, Dadgar‐Kiani, Ehsan, Catto, Francesca, Voigt, Fabian F, Trevisan, Chiara, Bichsel, Oliver, Shirani, Hamid, Nilsson, K Peter R, Frontzek, Karl J, Paganetti, Paolo, Helmchen, Fritjof, Lee, Jin Hyung, Aguzzi, Adriano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832821/ https://www.ncbi.nlm.nih.gov/pubmed/36382364 http://dx.doi.org/10.15252/emmm.202216789 |
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