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Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions

C‐reactive protein (CRP) is a marker of acute inflammation and modulator of host defense against infections. CRP exists in conformationally distinct forms that exhibit opposing biological functions and could amplify tissue damage. Therefore, therapies that efficiently target the deleterious actions...

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Detalles Bibliográficos
Autor principal: Filep, János G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832832/
https://www.ncbi.nlm.nih.gov/pubmed/36465053
http://dx.doi.org/10.15252/emmm.202217003