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Disease modification and symptom relief in osteoarthritis using a mutated GCP‐2/CXCL6 chemokine

We showed that the chemokine receptor C‐X‐C Motif Chemokine Receptor 2 (CXCR2) is essential for cartilage homeostasis. Here, we reveal that the CXCR2 ligand granulocyte chemotactic protein 2 (GCP‐2) was expressed, during embryonic development, within the prospective permanent articular cartilage, bu...

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Detalles Bibliográficos
Autores principales: Caxaria, Sara, Kouvatsos, Nikolaos, Eldridge, Suzanne E, Alvarez‐Fallas, Mario, Thorup, Anne‐Sophie, Cici, Daniela, Barawi, Aida, Arshed, Ammaarah, Strachan, Danielle, Carletti, Giulia, Huang, Xinying, Bharde, Sabah, Deniz, Melody, Wilson, Jacob, Thomas, Bethan L, Pitzalis, Costantino, Cantatore, Francesco Paolo, Sayilekshmy, Manasi, Sikandar, Shafaq, Luyten, Frank P, Pap, Thomas, Sherwood, Joanna C, Day, Anthony J, Dell'Accio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832835/
https://www.ncbi.nlm.nih.gov/pubmed/36507558
http://dx.doi.org/10.15252/emmm.202216218