A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein

C‐reactive protein (CRP) is an early‐stage acute phase protein and highly upregulated in response to inflammatory reactions. We recently identified a novel mechanism that leads to a conformational change from the native, functionally relatively inert, pentameric CRP (pCRP) structure to a pentameric...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeller, Johannes, Cheung Tung Shing, Karen S, Nero, Tracy L, McFadyen, James D, Krippner, Guy, Bogner, Balázs, Kreuzaler, Sheena, Kiefer, Jurij, Horner, Verena K, Braig, David, Danish, Habiba, Baratchi, Sara, Fricke, Mark, Wang, Xiaowei, Kather, Michel G, Kammerer, Bernd, Woollard, Kevin J, Sharma, Prerna, Morton, Craig J, Pietersz, Geoffrey, Parker, Michael W, Peter, Karlheinz, Eisenhardt, Steffen U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832874/
https://www.ncbi.nlm.nih.gov/pubmed/36468184
http://dx.doi.org/10.15252/emmm.202216236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832874/
https://www.ncbi.nlm.nih.gov/pubmed/36468184
http://dx.doi.org/10.15252/emmm.202216236

Ejemplares similares