Global insights into the fine tuning of human A(2A)AR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR

G protein-coupled receptor (GPCR) conformational plasticity enables formation of ternary signaling complexes with intracellular proteins in response to binding extracellular ligands. We investigate the dynamic process of GPCR complex formation in solution with the human A(2A) adenosine receptor (A(2...

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Detalles Bibliográficos
Autores principales: Ferré, Guillaume, Anazia, Kara, Silva, Larissa O., Thakur, Naveen, Ray, Arka P., Eddy, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832913/
https://www.ncbi.nlm.nih.gov/pubmed/36543140
http://dx.doi.org/10.1016/j.celrep.2022.111844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832913/
https://www.ncbi.nlm.nih.gov/pubmed/36543140
http://dx.doi.org/10.1016/j.celrep.2022.111844

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