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High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state
Cardiac contraction depends on molecular interactions among sarcomeric proteins coordinated by the rising and falling intracellular Ca(2+) levels. Cardiac thin filament (cTF) consists of two strands composed of actin, tropomyosin (Tm), and equally spaced troponin (Tn) complexes forming regulatory un...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832952/ https://www.ncbi.nlm.nih.gov/pubmed/36712934 http://dx.doi.org/10.1093/pnasnexus/pgac298 |