Accidental acquisition of a rescued Japanese encephalitis virus with unspliced introns in the viral genome when using an intron-based stabilization approach

The intron-based stabilization approach is a very useful strategy for construction of stable flavivirus infectious clones. SA(14)-14-2 is a highly attenuated Japanese encephalitis (JE) live vaccine strain that has been widely used in China since 1989. To develop safe and effective recombinant vaccin...

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Detalles Bibliográficos
Autores principales: Huang, Ying, Xu, Hongshan, Liu, Shan, Lu, Jiansheng, Jia, Lili, Li, Yuhua, Wang, Rong, Yang, Peng, Yu, Yongxin, Yang, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833022/
https://www.ncbi.nlm.nih.gov/pubmed/36629974
http://dx.doi.org/10.1007/s00705-022-05697-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833022/
https://www.ncbi.nlm.nih.gov/pubmed/36629974
http://dx.doi.org/10.1007/s00705-022-05697-z

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