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Water-Reaching Platform for Longitudinal Assessment of Cortical Activity and Fine Motor Coordination Defects in a Huntington Disease Mouse Model

Huntington disease (HD), caused by dominantly inherited expansions of a CAG repeat results in characteristic motor dysfunction. Although gross motor defects have been extensively characterized in multiple HD mouse models using tasks such as rotarod and beam walking, less is known about forelimb defi...

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Detalles Bibliográficos
Autores principales: Wang, Yundi, Sepers, Marja D., Xiao, Dongsheng, Raymond, Lynn A., Murphy, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833054/
https://www.ncbi.nlm.nih.gov/pubmed/36596592
http://dx.doi.org/10.1523/ENEURO.0452-22.2022