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Coronary atherosclerosis severity is closely associated with decreased GLP-1R positivity among CD16(+) pro-inflammatory and patrolling monocyte subsets

BACKGROUND AND AIMS: Glucagon Like Peptide-1 Receptor (GLP-1R) activation reduces pro-inflammatory responses of human monocytes, their accumulation in the vascular wall and foam cell formation inhibiting atherosclerogenesis. This suggests that reduction of circulating GLP-1-1R positive monocytes may...

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Detalles Bibliográficos
Autores principales: Bloch, Olga, Blatt, Alex, Appel, Michael Y., Ben Yehudah, Gilad, Cantrell, Dror, Goldberg, Michael, Love, Itamar, Khadija, Haitham Abu, Rapoport, Micha J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833237/
https://www.ncbi.nlm.nih.gov/pubmed/36643724
http://dx.doi.org/10.1016/j.athplu.2021.10.001