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TACE/ADAM17 substrates associate with ACS (Ep-CAM, HB-EGF) and follow-up MACE (TNFR1 and TNFR2)

BACKGROUND AND AIMS: TACE/ADAM17 is a membrane bound metalloprotease, which cleaves substrates involved in immune and inflammatory responses and plays a role in coronary artery disease (CAD). We measured TACE and its substrates in CAD patients to identify potential biomarkers within this molecular p...

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Detalles Bibliográficos
Autores principales: Chemaly, Melody, McAllister, Roisin, Peace, Aaron, Bjourson, Anthony John, Watterson, Steve, Parton, Andrew, Clauss, Matthias, McGilligan, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833260/
https://www.ncbi.nlm.nih.gov/pubmed/36643799
http://dx.doi.org/10.1016/j.athplu.2022.09.001