Downregulation of Stearoyl-CoA Desaturase 1 (SCD-1) Promotes Resistance to Imatinib in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a malignant hematopoietic stem cell disease resulting in the fusion of BCR and ABL genes and characterized by the presence of the reciprocal translocation t(9;22)(q34;q11). BCR-ABL, a product of the BCR-ABL fusion gene, is a structurally active tyrosine kinase and p...

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Detalles Bibliográficos
Autores principales: Altinok Gunes, Buket, Hekmatshoar, Yalda, Ozkan, Tulin, Bozkurt, Sureyya, Erdogan Aydos, O. Sena, Buyukasik, Yahya, Aladag, Elifcan, Sunguroglu, Asuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833301/
https://www.ncbi.nlm.nih.gov/pubmed/36660357
http://dx.doi.org/10.4084/MJHID.2023.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833301/
https://www.ncbi.nlm.nih.gov/pubmed/36660357
http://dx.doi.org/10.4084/MJHID.2023.008

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