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Development of hidden Markov modeling method for molecular orientations and structure estimation from high-speed atomic force microscopy time-series images
High-speed atomic force microscopy (HS-AFM) is a powerful technique for capturing the time-resolved behavior of biomolecules. However, structural information in HS-AFM images is limited to the surface geometry of a sample molecule. Inferring latent three-dimensional structures from the surface geome...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833559/ https://www.ncbi.nlm.nih.gov/pubmed/36580448 http://dx.doi.org/10.1371/journal.pcbi.1010384 |