Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors

Parvovirus B19 (B19V) infects human erythroid progenitor cells (EPCs) and causes several hematological disorders and fetal hydrops. Amino acid (aa) 5–68 of minor capsid protein VP1 (VP1u(5–68aa)) is the minimal receptor binding domain for B19V to enter EPCs. Here, we carried out a genome-wide CRISPR...

Descripción completa

Detalles Bibliográficos
Autores principales: Ning, Kang, Zou, Wei, Xu, Peng, Cheng, Fang, Zhang, Elizabeth Yan, Zhang-Chen, Aaron, Kleiboeker, Steve, Qiu, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833669/
https://www.ncbi.nlm.nih.gov/pubmed/36630517
http://dx.doi.org/10.1126/sciadv.ade0869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833669/
https://www.ncbi.nlm.nih.gov/pubmed/36630517
http://dx.doi.org/10.1126/sciadv.ade0869

Ejemplares similares