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A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

BACKGROUND AND AIMS: Colon cancer can occur sporadically or in the setting of chronic inflammation, such as in patients with inflammatory bowel disease. We previously showed that A20, a critical negative regulator of tumor necrosis factor signal transduction, could regulate sporadic colon cancer dev...

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Detalles Bibliográficos
Autores principales: Basta, David W., Vong, Mandy, Beshimova, Adolat, Nakamura, Brooke N., Rusu, Iulia, Kattah, Michael G., Shao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833806/
https://www.ncbi.nlm.nih.gov/pubmed/36636264
http://dx.doi.org/10.1016/j.gastha.2022.09.004