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UHPLC–MS/MS method for simultaneous quantification of doripenem, meropenem, ciprofloxacin, levofloxacin, pazufloxacin, linezolid, and tedizolid in filtrate during continuous renal replacement therapy

BACKGROUND: Since severe infections frequently cause acute kidney injury (AKI), continuous renal replacement therapy (CRRT) is often initiated for regulation of inflammatory mediators and renal support. Thus, it is necessary to decide the antibiotic dosage considering the CRRT clearance in addition...

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Detalles Bibliográficos
Autores principales: Kai, Makoto, Tanaka, Ryota, Suzuki, Yosuke, Goto, Koji, Ohchi, Yoshifumi, Yasuda, Norihisa, Tatsuta, Ryosuke, Kitano, Takaaki, Itoh, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833962/
https://www.ncbi.nlm.nih.gov/pubmed/36525363
http://dx.doi.org/10.1002/jcla.24815