Kv1.3 Channel Blockade Improves Inflammatory Profile, Reduces Cardiac Electrical Remodeling, and Prevents Arrhythmia in Type 2 Diabetic Rats

PURPOSE: Kv1.3 channel regulates the activity of lymphocytes, macrophages, or adipose tissue and its blockade reduces inflammatory cytokine secretion and improves insulin sensitivity in animals with metabolic syndrome and in genetically obese mice. Thus, Kv1.3 blockade could be a strategy for the tr...

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Detalles Bibliográficos
Autores principales: Zayas-Arrabal, Julián, Alquiza, Amaia, Rodríguez-de-Yurre, Ainhoa, Echeazarra, Leyre, Fernández-López, Víctor, Gallego, Mónica, Casis, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834174/
https://www.ncbi.nlm.nih.gov/pubmed/34623540
http://dx.doi.org/10.1007/s10557-021-07264-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834174/
https://www.ncbi.nlm.nih.gov/pubmed/34623540
http://dx.doi.org/10.1007/s10557-021-07264-1

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