The HAPSTR2 retrogene buffers stress signaling and resilience in mammals

We recently identified HAPSTR1 (C16orf72) as a key component in a novel pathway which regulates the cellular response to molecular stressors, such as DNA damage, nutrient scarcity, and protein misfolding. Here, we identify a functional paralog to HAPSTR1: HAPSTR2. HAPSTR2 formed early in mammalian e...

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Detalles Bibliográficos
Autores principales: Amici, David R., Cingoz, Harun, Alasady, Milad J., Alhayek, Sammy, Phoumyvong, Claire M., Sahni, Nidhi, Yi, S. Stephen, Mendillo, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834230/
https://www.ncbi.nlm.nih.gov/pubmed/36631436
http://dx.doi.org/10.1038/s41467-022-35697-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834230/
https://www.ncbi.nlm.nih.gov/pubmed/36631436
http://dx.doi.org/10.1038/s41467-022-35697-1

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