The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family

The RING-between-RING (RBR) E3 ubiquitin ligase family in humans comprises 14 members and is defined by a two-step catalytic mechanism in which ubiquitin is first transferred from an E2 ubiquitin-conjugating enzyme to the RBR active site and then to the substrate. To define the core features of this...

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Detalles Bibliográficos
Autores principales: Wang, Xiangyi S., Cotton, Thomas R., Trevelyan, Sarah J., Richardson, Lachlan W., Lee, Wei Ting, Silke, John, Lechtenberg, Bernhard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834252/
https://www.ncbi.nlm.nih.gov/pubmed/36631489
http://dx.doi.org/10.1038/s41467-023-35871-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834252/
https://www.ncbi.nlm.nih.gov/pubmed/36631489
http://dx.doi.org/10.1038/s41467-023-35871-z

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