Oxidative stress-induced MMP- and γ-secretase-dependent VE-cadherin processing is modulated by the proteasome and BMP9/10

Classical cadherins, including vascular endothelial (VE)-cadherin, are targeted by matrix metalloproteinases (MMPs) and γ-secretase during adherens junction (AJ) disassembly, a mechanism that might have relevance for endothelial cell (EC) integrity and vascular homeostasis. Here, we show that oxidat...

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Detalles Bibliográficos
Autores principales: Ivaldo, Caterina, Passalacqua, Mario, Furfaro, Anna Lisa, d’Abramo, Cristina, Ruiz, Santiago, Chatterjee, Prodyot K., Metz, Christine N., Nitti, Mariapaola, Marambaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834263/
https://www.ncbi.nlm.nih.gov/pubmed/36631513
http://dx.doi.org/10.1038/s41598-022-27308-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834263/
https://www.ncbi.nlm.nih.gov/pubmed/36631513
http://dx.doi.org/10.1038/s41598-022-27308-2

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