Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation

B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using monoclonal antibodies (mAbs) have resulted in failure in some cases. Nanobodies (NBs), single-domain antibodies with low...

Descripción completa

Detalles Bibliográficos
Autores principales: Poustforoosh, Alireza, Faramarz, Sanaz, Negahdaripour, Manica, Hashemipour, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834265/
https://www.ncbi.nlm.nih.gov/pubmed/36631511
http://dx.doi.org/10.1038/s41598-023-27926-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834265/
https://www.ncbi.nlm.nih.gov/pubmed/36631511
http://dx.doi.org/10.1038/s41598-023-27926-4

Ejemplares similares