PDGF inhibits BMP2-induced bone healing

Bone regeneration depends on a pool of bone/cartilage stem/progenitor cells and signaling mechanisms regulating their differentiation. Using in vitro approach, we have shown that PDGF signaling through PDGFRβ inhibits BMP2-induced osteogenesis, and significantly attenuates expression of BMP2 target...

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Detalles Bibliográficos
Autores principales: Novak, Sanja, Madunic, Josip, Shum, Laura, Vucetic, Milan, Wang, Xi, Tanigawa, Hitoshi, Ghosh, Mallika, Sanjay, Archana, Kalajzic, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834334/
https://www.ncbi.nlm.nih.gov/pubmed/36631491
http://dx.doi.org/10.1038/s41536-023-00276-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834334/
https://www.ncbi.nlm.nih.gov/pubmed/36631491
http://dx.doi.org/10.1038/s41536-023-00276-5

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