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Mast cell chymase is in contact with melanoma cells in vivo and it detaches melanoma cells from the substratum in vitro

BACKGROUND: Mast cell chymase, a chymotryptic serine proteinase, is a powerful enzyme that may liberate adherent tumor cells thereby promoting tumor spread. METHODS: This study investigated interactions between cells containing immunoreactive chymase and melanoma cells in 101 melanoma and 50 nevus s...

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Detalles Bibliográficos
Autores principales: Siiskonen, Hanna, Harvima, Ilkka T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834600/
https://www.ncbi.nlm.nih.gov/pubmed/36644179
http://dx.doi.org/10.21037/tcr-22-1688