A humanized anti‐cocaine mAb antagonizes the cardiovascular effects of cocaine in rats

The recombinant monoclonal anti‐cocaine antibody, h2E2, sequesters cocaine in plasma increasing concentrations more than 10‐fold. The increased levels of cocaine in the plasma could have detrimental peripheral effects, particularly on the cardiovascular system. We investigated the duration and magni...

Descripción completa

Detalles Bibliográficos
Autores principales: Koch, Sheryl E., Marckel, Jordan A., Rubinstein, Jack, Norman, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834608/
https://www.ncbi.nlm.nih.gov/pubmed/36631960
http://dx.doi.org/10.1002/prp2.1045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834608/
https://www.ncbi.nlm.nih.gov/pubmed/36631960
http://dx.doi.org/10.1002/prp2.1045

Ejemplares similares