Co‐occurring KEAP1 and TP53 mutations in lung squamous cell carcinoma induced primary resistance to thoracic radiotherapy: A case report

In lung squamous cell carcinoma, KEAP1 mutations frequently coexist with TP53 mutations. A preclinical model showed that mutations leading to the activation of the KEAP1–NRF2 pathway contribute to clinical radioresistance. However, there have been few clinical reports on the association between the...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishimura, Rumi, Yoshida, Tatsuya, Torasawa, Masahiro, Kashihara, Tairo, Ohe, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834690/
https://www.ncbi.nlm.nih.gov/pubmed/36453575
http://dx.doi.org/10.1111/1759-7714.14751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834690/
https://www.ncbi.nlm.nih.gov/pubmed/36453575
http://dx.doi.org/10.1111/1759-7714.14751

Ejemplares similares