Bacterial expression of a designed single‐chain IL‐10 prevents severe lung inflammation

Interleukin‐10 (IL‐10) is an anti‐inflammatory cytokine that is active as a swapped domain dimer and is used in bacterial therapy of gut inflammation. IL‐10 can be used as treatment of a wide range of pulmonary diseases. Here we have developed a non‐pathogenic chassis (CV8) of the human lung bacteri...

Descripción completa

Detalles Bibliográficos
Autores principales: Montero‐Blay, Ariadna, Blanco, Javier Delgado, Rodriguez‐Arce, Irene, Lastrucci, Claire, Piñero‐Lambea, Carlos, Lluch‐Senar, Maria, Serrano, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834763/
https://www.ncbi.nlm.nih.gov/pubmed/36598022
http://dx.doi.org/10.15252/msb.202211037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834763/
https://www.ncbi.nlm.nih.gov/pubmed/36598022
http://dx.doi.org/10.15252/msb.202211037

Ejemplares similares