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Bacterial expression of a designed single‐chain IL‐10 prevents severe lung inflammation
Interleukin‐10 (IL‐10) is an anti‐inflammatory cytokine that is active as a swapped domain dimer and is used in bacterial therapy of gut inflammation. IL‐10 can be used as treatment of a wide range of pulmonary diseases. Here we have developed a non‐pathogenic chassis (CV8) of the human lung bacteri...
Autores principales: | Montero‐Blay, Ariadna, Blanco, Javier Delgado, Rodriguez‐Arce, Irene, Lastrucci, Claire, Piñero‐Lambea, Carlos, Lluch‐Senar, Maria, Serrano, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834763/ https://www.ncbi.nlm.nih.gov/pubmed/36598022 http://dx.doi.org/10.15252/msb.202211037 |
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