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Single-cell transcriptomics and network pharmacology reveal therapeutic targets of Jianpi Yiqi Bugan Yishen decoction in immune cell subsets of children with myasthenia gravis

BACKGROUND: Myasthenia gravis (MG) is an acquired autoimmune disease of the neuromuscular junction. As immunosuppressive agents used to treat MG have a significant impact on the growth and development of children, treatment is extremely challenging. Jianpi Yiqi Bugan Yishen Decoction (JYBYD) has bee...

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Detalles Bibliográficos
Autores principales: Liu, Peng, Qi, Guoyan, Gu, Shanshan, Dong, Huimin, Liu, Chaoying, Yang, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834954/
https://www.ncbi.nlm.nih.gov/pubmed/36643680
http://dx.doi.org/10.21037/tp-22-593