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Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients

Neutralizing antibody (nAb) responses are attenuated in solid organ transplant recipients (SOTRs) despite severe acute respiratory syndrome-coronavirus-2 vaccination. Preexposure prophylaxis (PrEP) with the antibody combination tixagevimab and cilgavimab (T+C) might augment immunoprotection, yet in...

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Detalles Bibliográficos
Autores principales: Karaba, Andrew H., Kim, Jake D., Chiang, Teresa P-Y., Alejo, Jennifer L., Sitaras, Ioannis, Abedon, Aura T., Eby, Yolanda, Johnston, Trevor Scott, Li, Maggie, Aytenfisu, Tihitina, Hussey, Casey, Jefferis, Alexa, Fortune, Nicole, Abedon, Rivka, Thomas, Letitia, Habtehyimer, Feben, Ruff, Jessica, Warren, Daniel S., Avery, Robin K., Clarke, William A., Pekosz, Andrew, Massie, Allan B., Tobian, Aaron A.R., Segev, Dorry L., Werbel, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. on behalf of American Society of Transplantation & American Society of Transplant Surgeons. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835002/
https://www.ncbi.nlm.nih.gov/pubmed/36906295
http://dx.doi.org/10.1016/j.ajt.2022.11.002