Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses

PURPOSE: Malignant gliomas have a highly immune-suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics. Therefore, the current study evaluated a therapeutic protocol designed to overcome the immune barrier by combining myeloid cell–targeted immu...

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Detalles Bibliográficos
Autores principales: Ammons, Dylan T., Guth, Amanda, Rozental, Aaron J., Kurihara, Jade, Marolf, Angela J., Chow, Lyndah, Griffin, John F., Makii, Rebecca, MacQuiddy, Brittany, Boss, Mary-Keara, Regan, Daniel P., Frank, Chad, McGrath, Stephanie, Packer, Rebecca A., Dow, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835010/
https://www.ncbi.nlm.nih.gov/pubmed/36644324
http://dx.doi.org/10.1158/2767-9764.CRC-22-0388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835010/
https://www.ncbi.nlm.nih.gov/pubmed/36644324
http://dx.doi.org/10.1158/2767-9764.CRC-22-0388

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