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Developmental pharmacokinetics of indomethacin in preterm neonates: Severely decreased drug clearance in the first week of life

Indomethacin is used commonly in preterm neonates for the prevention of intracranial hemorrhage and closure of an abnormally open cardiac vessel. Due to biomedical advances, the infants who receive this drug in the neonatal intensive care unit setting have become younger, smaller, and less mature (m...

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Detalles Bibliográficos
Autores principales: Krzyzanski, Wojciech, Stockard, Bradley, Gaedigk, Andrea, Scott, Allison, Nolte, Whitney, Gibson, Kim, Leeder, J. Steven, Lewis, Tamorah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835126/
https://www.ncbi.nlm.nih.gov/pubmed/36309972
http://dx.doi.org/10.1002/psp4.12881