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Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools

The pharmacokinetics (PKs) and safety of medications in particular groups can be predicted using the physiologically‐based pharmacokinetic (PBPK) model. Using the PBPK model may enable safe pediatric clinical trials and speed up the process of new drug research and development, especially for childr...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Dun, Jiening, Chen, Xiao, Xiang, Bai, Dang, Yunjie, Cao, Deying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835135/
https://www.ncbi.nlm.nih.gov/pubmed/36330677
http://dx.doi.org/10.1002/psp4.12883