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Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools
The pharmacokinetics (PKs) and safety of medications in particular groups can be predicted using the physiologically‐based pharmacokinetic (PBPK) model. Using the PBPK model may enable safe pediatric clinical trials and speed up the process of new drug research and development, especially for childr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835135/ https://www.ncbi.nlm.nih.gov/pubmed/36330677 http://dx.doi.org/10.1002/psp4.12883 |