Cargando…
Predicting the correct dose in children: Role of computational Pediatric Physiological‐based pharmacokinetics modeling tools
The pharmacokinetics (PKs) and safety of medications in particular groups can be predicted using the physiologically‐based pharmacokinetic (PBPK) model. Using the PBPK model may enable safe pediatric clinical trials and speed up the process of new drug research and development, especially for childr...
Autores principales: | Zhou, Xu, Dun, Jiening, Chen, Xiao, Xiang, Bai, Dang, Yunjie, Cao, Deying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835135/ https://www.ncbi.nlm.nih.gov/pubmed/36330677 http://dx.doi.org/10.1002/psp4.12883 |
Ejemplares similares
-
Physiologically based pharmacokinetic modeling of daptomycin dose optimization in pediatric patients with renal impairment
por: Ye, Lingling, et al.
Publicado: (2022) -
Physiologically based pharmacokinetic modeling of tadalafil to inform pediatric dose selection in children with pulmonary arterial hypertension
por: Rehmel, Jessica, et al.
Publicado: (2021) -
Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors
por: Huang, Weize, et al.
Publicado: (2022) -
A Retrospective Evaluation of Allometry, Population Pharmacokinetics, and Physiologically‐Based Pharmacokinetics for Pediatric Dosing Using Clearance as a Surrogate
por: Wu, Qier, et al.
Publicado: (2019) -
Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
por: Rashid, Memoona, et al.
Publicado: (2020)