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Forced Intercalation Peptide Nucleic Acid Probes for the Detection of an Adenosine-to-Inosine Modification

[Image: see text] The deamination of adenosine to inosine is an important modification in nucleic acids that functionally recodes the identity of the nucleobase to a guanosine. Current methods to analyze and detect this single nucleotide change, such as sequencing and PCR, typically require time-con...

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Detalles Bibliográficos
Autores principales: Swenson, Colin S., Argueta-Gonzalez, Hector S., Sterling, Sierra A., Robichaux, Ryan, Knutson, Steve D., Heemstra, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835161/
https://www.ncbi.nlm.nih.gov/pubmed/36643573
http://dx.doi.org/10.1021/acsomega.2c03568