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Network Analysis of Molecular Dynamics Sectors in the p53 Protein

[Image: see text] Design of allosteric regulators is an emergent field in the area of drug discovery holding promise for currently untreated diseases. Allosteric regulators bind to a protein in one location and affect a distant site. The ubiquitous presence of allosteric effectors in biology and the...

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Detalles Bibliográficos
Autores principales: Fabry, Jonathan D., Thayer, Kelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835189/
https://www.ncbi.nlm.nih.gov/pubmed/36643471
http://dx.doi.org/10.1021/acsomega.2c05635