CTP synthase 2 predicts inferior survival and mediates DNA damage response via interacting with BRCA1 in chronic lymphocytic leukemia

BACKGROUND: Cytidine triphosphate synthase 2 (CTPS2) is an essential metabolic enzyme that catalyzes the biosynthesis of CTP. CTP synthases contribute to lymphocytes proliferation and tumorigenesis, but the role of CTPS2 in chronic lymphocytic leukemia (CLL) remains undefined. METHODS: In silico ana...

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Detalles Bibliográficos
Autores principales: Hu, Xinting, Han, Yang, Liu, Jiarui, Wang, Hua, Tian, Zheng, Zhang, Xin, Zhang, Ya, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835321/
https://www.ncbi.nlm.nih.gov/pubmed/36635772
http://dx.doi.org/10.1186/s40164-022-00364-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835321/
https://www.ncbi.nlm.nih.gov/pubmed/36635772
http://dx.doi.org/10.1186/s40164-022-00364-0

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