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Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification

BACKGROUND: Our recent studies found that intestinal mechanical signals can regulate mucus synthesis and secretion of intestinal goblet cells through piezo type mechanosensitive ion channel component 1 (Piezo1), but the detailed molecular mechanisms remain to be investigated. Previous studies using...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Xiong, Yilin, Liu, Ying, Li, Gangping, Bai, Tao, Zheng, Gen, Hou, Xiaohua, Song, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835388/
https://www.ncbi.nlm.nih.gov/pubmed/36631841
http://dx.doi.org/10.1186/s13578-023-00952-5