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Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification
BACKGROUND: Our recent studies found that intestinal mechanical signals can regulate mucus synthesis and secretion of intestinal goblet cells through piezo type mechanosensitive ion channel component 1 (Piezo1), but the detailed molecular mechanisms remain to be investigated. Previous studies using...
Autores principales: | Xu, Yan, Xiong, Yilin, Liu, Ying, Li, Gangping, Bai, Tao, Zheng, Gen, Hou, Xiaohua, Song, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835388/ https://www.ncbi.nlm.nih.gov/pubmed/36631841 http://dx.doi.org/10.1186/s13578-023-00952-5 |
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