Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin

Declining nicotinamide adenine dinucleotide (NAD(+)) concentration in the brain during aging contributes to metabolic and cellular dysfunction and is implicated in the pathogenesis of aging‐associated neurological disorders. Experimental therapies aimed at boosting brain NAD(+) levels normalize seve...

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Detalles Bibliográficos
Autores principales: Vreones, Michael, Mustapic, Maja, Moaddel, Ruin, Pucha, Krishna A., Lovett, Jacqueline, Seals, Douglas R., Kapogiannis, Dimitrios, Martens, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835564/
https://www.ncbi.nlm.nih.gov/pubmed/36515353
http://dx.doi.org/10.1111/acel.13754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835564/
https://www.ncbi.nlm.nih.gov/pubmed/36515353
http://dx.doi.org/10.1111/acel.13754

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