Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal

Antiretroviral drugs have dramatically improved the prognosis of HIV‐infected patients, with strikingly reduced morbidity and mortality. However, long‐term use can be associated with signs of premature aging. Highly active antiretroviral therapy generally comprises two nucleoside reverse transcripta...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuehnemann, Chisaka, Hughes, Jun‐Wei B., Desprez, Pierre‐Yves, Melov, Simon, Wiley, Christopher D., Campisi, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835573/
https://www.ncbi.nlm.nih.gov/pubmed/36539941
http://dx.doi.org/10.1111/acel.13750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835573/
https://www.ncbi.nlm.nih.gov/pubmed/36539941
http://dx.doi.org/10.1111/acel.13750

Ejemplares similares