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Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal
Antiretroviral drugs have dramatically improved the prognosis of HIV‐infected patients, with strikingly reduced morbidity and mortality. However, long‐term use can be associated with signs of premature aging. Highly active antiretroviral therapy generally comprises two nucleoside reverse transcripta...
Autores principales: | Kuehnemann, Chisaka, Hughes, Jun‐Wei B., Desprez, Pierre‐Yves, Melov, Simon, Wiley, Christopher D., Campisi, Judith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835573/ https://www.ncbi.nlm.nih.gov/pubmed/36539941 http://dx.doi.org/10.1111/acel.13750 |
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