High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP

Autophagy defects accelerate aging, while stimulation of autophagy decelerates aging. Acyl‐coenzyme A binding protein (ACBP), which is encoded by a diazepam‐binding inhibitor (DBI), acts as an extracellular feedback regulator of autophagy. As shown here, knockout of the gene coding for the yeast ort...

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Detalles Bibliográficos
Autores principales: Montégut, Léa, Joseph, Adrien, Chen, Hui, Abdellatif, Mahmoud, Ruckenstuhl, Christoph, Motiño, Omar, Lambertucci, Flavia, Anagnostopoulos, Gerasimos, Lachkar, Sylvie, Dichtinger, Silvia, Maiuri, Maria Chiara, Goldwasser, François, Blanchet, Benoit, Fumeron, Frédéric, Martins, Isabelle, Madeo, Frank, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835587/
https://www.ncbi.nlm.nih.gov/pubmed/36510662
http://dx.doi.org/10.1111/acel.13751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835587/
https://www.ncbi.nlm.nih.gov/pubmed/36510662
http://dx.doi.org/10.1111/acel.13751

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