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Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase
Anthranilate phosphoribosyltransferase catalyses the second reaction in the biosynthesis of tryptophan from chorismate in microorganisms and plants. The enzyme is homodimeric with the active site located in the hinge region between two domains. A range of structures in complex with the substrates, s...
Autores principales: | Scully, Thomas W., Jiao, Wanting, Mittelstädt, Gerd, Parker, Emily J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835598/ https://www.ncbi.nlm.nih.gov/pubmed/36633281 http://dx.doi.org/10.1098/rstb.2022.0039 |
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