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Crystal structures of ‘ALternative Isoinformational ENgineered’ DNA in B-form

The first structural model of duplex DNA reported in 1953 by Watson & Crick presented the double helix in B-form, the form that genomic DNA exists in much of the time. Thus, artificial DNA seeking to mimic the properties of natural DNA should also be able to adopt B-form. Using a host–guest syst...

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Detalles Bibliográficos
Autores principales: Shukla, Madhura S., Hoshika, Shuichi, Benner, Steven A., Georgiadis, Millie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835606/
https://www.ncbi.nlm.nih.gov/pubmed/36633282
http://dx.doi.org/10.1098/rstb.2022.0028