Gentamycin Rationally Repositioned to Inhibit miR-34a Ameliorates Oxidative Injury to PC12 Cells

[Image: see text] Ischemic stroke accompanies oxidative stress and cell death in the cerebral tissue. The microRNA miR-34a plays a pivotal role in this molecular pathology. This study presents the rational repositioning of aminoglycosidic antibiotics as miR-34a antagonists in order to assess their e...

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Detalles Bibliográficos
Autores principales: Izadi, Zhila, Barzegari, Ebrahim, Iranpanah, Amin, Sajadimajd, Soraya, Derakhshankhah, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835649/
https://www.ncbi.nlm.nih.gov/pubmed/36643496
http://dx.doi.org/10.1021/acsomega.2c06112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835649/
https://www.ncbi.nlm.nih.gov/pubmed/36643496
http://dx.doi.org/10.1021/acsomega.2c06112

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