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Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis

In multiple sclerosis and the experimental autoimmune encephalomyelitis (EAE) model, both resident microglia and infiltrating macrophages contribute to demyelination as well as spontaneous remyelination. Nevertheless, the specific roles of microglia versus macrophages are unknown. We investigated th...

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Detalles Bibliográficos
Autores principales: Montilla, Alejandro, Zabala, Alazne, Er-Lukowiak, Marco, Rissiek, Björn, Magnus, Tim, Rodriguez-Iglesias, Noelia, Sierra, Amanda, Matute, Carlos, Domercq, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835747/
https://www.ncbi.nlm.nih.gov/pubmed/36635255
http://dx.doi.org/10.1038/s41419-023-05551-3