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Genome-scale CRISPR screening in a single mouse liver

A complete understanding of the genetic determinants underlying mammalian physiology and disease is limited by the capacity for high-throughput genetic dissection in the living organism. Genome-wide CRISPR screening is a powerful method for uncovering the genetic regulation of cellular processes, bu...

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Detalles Bibliográficos
Autores principales: Keys, Heather R., Knouse, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835819/
https://www.ncbi.nlm.nih.gov/pubmed/36643909
http://dx.doi.org/10.1016/j.xgen.2022.100217