Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control

BACKGROUND: Radioimmunotherapy combines irradiation of tumor lesions with immunotherapy to achieve local and abscopal control of cancer. Most immunotherapy agents are given systemically, but strategies for delivering immunotherapy locally are under clinical scrutiny to maximize efficacy and avoid to...

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Detalles Bibliográficos
Autores principales: Rodriguez-Ruiz, Maria E, Serrano-Mendioroz, Irantzu, Garate-Soraluze, Eneko, Sánchez-Mateos, Paloma, Barrio-Alonso, Celia, Rodríguez López, Inmaculada, Diaz Pascual, Victor, Arbea Moreno, Leire, Alvarez, Maite, Sanmamed, Miguel F, Perez-Gracia, Jose Luis, Escuin-Ordinas, Helena, Quintero, Marisol, Melero, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835951/
https://www.ncbi.nlm.nih.gov/pubmed/36631161
http://dx.doi.org/10.1136/jitc-2022-005011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835951/
https://www.ncbi.nlm.nih.gov/pubmed/36631161
http://dx.doi.org/10.1136/jitc-2022-005011

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