Nasal epithelial cell culture fluorescence recovery after photobleaching predicts cystic fibrosis therapeutic response

BACKGROUND: Human nasal epithelial (HNE) cells can be sampled noninvasively and cultured to provide a model of the airway epithelium that reflects cystic fibrosis (CF) pathophysiology. We hypothesised that in vitro measures of HNE cell physiology would correlate directly with in vivo measures of lun...

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Detalles Bibliográficos
Autores principales: Corcoran, Timothy E., Bertrand, Carol A., Myerburg, Michael M., Weiner, Daniel J., Frizzell, Sheila A., Li, Anna, Agostini, Brittani, Parker, Robert S., Shapiro, Monica E., Muthukrishnan, Ashok, Hages, Nicholas D., Mulhern, Brian P., Pilewski, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835985/
https://www.ncbi.nlm.nih.gov/pubmed/36655223
http://dx.doi.org/10.1183/23120541.00382-2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9835985/
https://www.ncbi.nlm.nih.gov/pubmed/36655223
http://dx.doi.org/10.1183/23120541.00382-2022

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